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Ramivan (Roxithromycin)
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Ramivan

Ramivan is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. It is a white crystalline powder. Ramivan is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring.

Other names for this medication:
Aristomycin, Asmetic, Assoral, Azuril, Bazuctril, Bicofen, Biostatik, Cadithro, Crolix, Delos, Elrox, Erybros, Floxid, Infectoroxit, Klomicina, Ladlid, Makrodex, Monobac, Nirox, Odonticina, Overal, Pedilid, Ramivan, Redotrin, Remora, Rokilide, Roksimin, Roksolit, Rolid, Romac, Romyk, Rossitrol, Roxacine, Roxithromycine, Roxithromycinum, Roxitromicina, Rulid

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Also known as: Roxithromycin

Description

Ramivan is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Ramivan is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring. It is also currently undergoing clinical trials for the treatment of male-pattern hair loss.

Ramivan is available under several brandnames. Ramivan is not available in the United States. Ramivan is available in Australia, Israel and New Zealand. Ramivan has also been tested to possess antimalarial activity.

Ramivan prevents bacteria from growing, by interfering with their protein synthesis. Ramivan binds to the subunit 50S of the bacterial ribosome, and thus inhibits the synthesis of peptides. Ramivan has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila.

Dosage

Take Generic Ramivan by mouth with food. If you have trouble swallowing the tablet whole, it may be crushed or chewed with a little water. Swallow Generic Ramivan tablets whole with a glass of water. Generic Ramivan should be taken at least 15 minutes before food or on an empty stomach (i.e. more than 3 hours after a meal). Generic Ramivan works best if you take it on an empty stomach. For treating bacterial infections, Generic Ramivan is usually taken for 5 to 10 days. If you want to achieve most effective results do not stop taking Generic Ramivan suddenly.

Overdose

If you overdose Generic Ramivan and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep your tablets in the blister pack until it is time to take them. If you take the tablets out of the blister pack they may not keep well.

Keep the medicine in a cool, dry place where the temperature stays below 25 degrees C.

Do not store it or any other medicine in the bathroom, near a sink or on windowsill.

Do not leave it in the car. Heat and damp can destroy some medicines.

Keep it where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Side effects

The most common side effects associated with Ramivan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

The safety of roxithromycin has not been demonstrated in patients with impaired hepatic or renal function. Caution should be exercised if roxithromycin is administered to patients with impaired hepatic or renal function. If administered to patients with severe impaired hepatic function (eg. hepatic cirrhosis with jaundice and/or ascites), consideration should be given to reducing the daily dosage to half the usual dosage.

Prolonged or repeated use of antibiotics including roxithromycin may result in superinfection by resistant organisms. In the event of superinfection, roxithromycin should be discontinued and appropriate therapy instituted.

When indicated, incision, drainage or other appropriate surgical procedures should be performed in conjunction with antibiotic therapy.

Antibiotic associated pseudomembranous colitis has been reported with many antibiotics. A toxin produced by Clostridium difficile appears to be the primary cause. The severity of the colitis may range from mild to life threatening. It is important to consider this diagnosis in patients who develop diarrhoea or colitis in association with antibiotic use (this may occur up to several weeks after cessation of antibiotic therapy). Mild cases usually respond to drug discontinuation alone. However, in moderate to severe cases, appropriate therapy with a suitable oral antibacterial agent effective against Clostridium difficile should be considered. Fluids, electrolytes and protein replacement therapy should be provided when indicated.

Roxithromycin, like erythromycin, has been shown in vitro to elicit a concentration - dependent lengthening in cardiac action potential duration. Such an effect is manifested only at supra – therapeutic concentrations. Accordingly, the recommended doses should not be exceeded. In certain conditions macrolides, including roxithromycin, have the potential to prolong the QT interval. Therefore roxithromycin should be used with caution in patients with congenital prolongation of the QT interval, with ongoing proarrhythmic conditions (ie uncorrected hypokalemia or hypomagnesaemia, clinically significant bradycardia), and in patients receiving Class IA and III antiarrhythmic agents.

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The hippocampus and amygdala, due to their involvement in stress and emotion circuitries, have been subject to extensive investigations regarding the effect of CM. Retrospective review of post-LASIK ectasia patients referred to and treated at 3 corneal refractive surgery institutions in Sydney, Australia. Antimicrobial therapy has to be introduced early in the course of infection, must be adequate, essentially with a broad spectrum and prescribed at the right dosage. A mechanism of the augmentation of antibody response in vitro by 2-mercaptoethanol: facilitation of cystine uptake in murine lymphocytes. Our aim was to investigate the potential relationship between dynamic stress concentration at baseline and plaque rupture during acute coronary syndrome (ACS) several months later. Primary mental health is an orientation to care that addresses mental health needs of consumers on point of first contact with caregivers.

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Feasibility Study of Extended-Gate-Type Silicon Nanowire Field-Effect Transistors for Neural Recording. In patients with sickle cell disease, hyperhemolysis is a rare but life-threatening complication of transfusion. Study children rated lower in persistence or higher in negative reactivity in early childhood gained more weight between the ages of 4 and 15 years. The SD animals were sensitive to the weight-reducing effects of leptin (mean body mass decrease of 1.2 g over 7 days) and appetite-reducing effect of leptin (mean food intake decrease of 2.5 g over 7 days), whereas LD voles were resistant to the hormone treatment. Pancreatic islet response to dicarboxylic acid esters in rats with type 2 diabetes: enzymatic, metabolic and secretory aspects. Interplay between policy and science regarding low-dose antimicrobial use in livestock.

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Intraluminal aortic occlusion as a possible mechanism for controlling massive intra-abdominal hemorrhage. Bacillary prostatitis after intravesical immunotherapy: a rare adverse effect. Mycobacterium tuberculosis is a global health concern, causing over one million deaths a year. The First Case of Zika Virus Isolated from a Japanese Patient Who Returned to Japan from Fiji in 2016. When the clinician needs to prolong seizure duration in patients treated with valproate, interruption of the valproate treatment or an anesthetic agent other than propofol should be considered. This review attempts to estimate the contribution of different known work-related causes of lung cancer in the Norwegian male population in order to predict the potential of prevention of work-related cases. Minimal inhibitory concentrations (MICs) of penicillin G, cefamandole, tetracycline, clindamycin and metronidazole were determined against 42 isolates of anaerobic bacteria.

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